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221 South Main StreetMiddleton, MA 01949Inquire For Price

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Federal 30-year interest rate: 6.71% last updated on Sep 3, 2026
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This product uses the FRED® API but is not endorsed or certified by the Federal Reserve Bank of St. Louis.
  • $1List Price
  • 3.05Acreage
  • 1,820Square Feet

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Listed by Brian Reardon of Five Mark Realty Group LLC
Excellent opportunity to lease approximately 1,820 SF of well-appointed retail/service space with direct frontage on Route 114 (South Main Street), one of the North Shore's primary commercial corridors with traffic counts exceeding 30,000 vehicles per day. Previously occupied by a boutique med spa, the space is already built out with a welcoming reception and waiting area, multiple private treatment rooms, and two bathrooms, providing an attractive opportunity for a new tenant to occupy with minimal upfront build-out. The existing layout lends itself particularly well to medical, wellness, aesthetics, professional office, and other service-oriented concepts, subject to landlord and municipal approval. The space is located within an established and highly active commercial center featuring a strong mix of national and local tenants, including Starbucks, Salem Five Bank, and Btone Fitness. This complementary tenant mix helps generate consistent daily customer traffic and makes the center a well-known destination along the Route 114 corridor. The property offers excellent visibility and exposure along Route 114, convenient customer and employee parking in the shared on-site lots, and signage opportunities, including an available panel on the property's street pylon sign.

Property Details of 221 South Main Street

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The property listing data and information, or the Images, set forth herein were provided to MLS Property Information Network, Inc. (MLSPIN) from third party sources, including sellers, lessors and public records, and were compiled by MLSPIN. The property listing data and information, and the Images, are for the personal, non-commercial use of consumers having a good faith interest in purchasing or leasing listed properties of the type displayed to them and may not be used for any purpose other than to identify prospective properties which such consumers may have a good faith interest in purchasing or leasing. MLSPIN and its subscribers disclaim any and all representations and warranties as to the accuracy of the property listing data and information, or as to the accuracy of any of the Images, set forth herein.

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